Virginia Tech vs. Vandy Football Prediction & Odds - Sept. 6

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The Vanderbilt Commodores (1-0) visit the Virginia Tech Hokies (0-1) at Lane Stadium on Saturday, September 6, 2025.

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Virginia Tech vs. Vanderbilt Matchup Info

  • Game date: Saturday, September 6, 2025
  • Game time: 7:30 p.m. ET
  • Location: Blacksburg, Virginia
  • Venue: Lane Stadium
  • TV channel: ACC Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Virginia Tech vs. Vanderbilt Odds and Prediction

  • Spread favorite: Hokies (-2.5)
  • Moneyline: Hokies (-128), Commodores (+108)
  • Total: 45 points
  • Pick ATS: Virginia Tech (-2.5)
  • Pick OU: Over (45)
  • Prediction: Virginia Tech 29, Vanderbilt 21

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Virginia Tech vs. Vanderbilt Betting Records and Insights

  • Virginia Tech has compiled a 0-1-0 record against the spread this season.
  • Vanderbilt has won all one of its games against the spread this year.
  • Vanderbilt has yet to hit the over in any game this year.

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